XPS spectrum showed distinct silver peaks on the nanoparticles’ surface. X-ray diffraction technique was used to characterize crystalline silver nanoparticles face-centered cubic structure. The NP size uniformity was determined by the SEM and TEM analysis. Hence here we give the detailed description on the recent developments of glucose sensors based on noble metal nanoparticles and real-time applications for the detection. The silver nanoparticles have a size of approximately 25 nm. Though various nanoparticles are available in earlier reports, this book chapter is mainly focused on noble metal (Ag, Au) nanoparticles as glucose sensors for detecting the desired bioanalyte of interest due to its distinctive properties. Various metal oxide nanoparticles such as CuO, La 2O 3, etc., and carbon-based materials are used for biosensing. A series of methods have been developed to measure blood glucose levels such as non-enzymatic electrochemical detection, colorimetric detection, surface-enhanced Raman scattering (SERS), and fluorescence detection. Many efforts are made by humans toward synthesis of nonenzymatic glucose sensing materials mainly based on noble nanostructured materials such as Ag, Au, etc. CoreShell Gold/Silver Nanoparticles for Localized Surface Plasmon Resonance-Based Naked-Eye Toxin Biosensing Alexis Loiseau, Lu Zhang, David Hu, Michle Salmain, Yacine Mazouzi, Raphal Flack, Bo Liedberg, and Souhir Boujday Cite this: ACS Appl. Simple strategies for producing silver and gold nanoparticles (AgNP and AuNP) along with the corresponding core shell nanoparticles (AuAg and AgAu) by reduction of the metal salts. Even though tracking the glucose in diabetic patient is at peak and more sensing strips are available, researchers are mainly focused on developing nonenzymatic glucose sensor, whereas enzyme-based glucose sensor suffers from many drawbacks, such as high cost, pH value, humidity, temperature, and poor long-term stability. This number will increase to about 592 million by 2035. By 2014, there were about 422 million adults with diabetes globally. During last few decades environmental issues are at the topmost level around the world causing unfortunate health and energy-related problems. In this work, spherical copper (core) - silver (shell) nanoparticles with diameter of 40-50 nm were synthesized through polyol successive reduction process.
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